Actiq

Overview of Actiq (Fentanyl Citrate Oral Transmucosal Lozenge)

Actiq is a proprietary oral transmucosal fentanyl citrate (OTFC) formulation designed to deliver rapid analgesia for breakthrough cancer pain in patients who are already opioid-tolerant. The lozenge is applied to the buccal mucosa, allowing fentanyl — a highly potent synthetic opioid — to be absorbed directly into the bloodstream, bypassing first-pass hepatic metabolism and providing faster onset of action compared to many conventional oral analgesics.

Fentanyl, the active compound in Actiq, belongs to the 4-anilidopiperidine class of opioids and is estimated to be approximately 80–100 times more potent than morphine on a per-milligram basis. Its pharmacokinetic profile, including rapid onset (typically 5–15 minutes) and a relatively short duration of action, makes it particularly valuable in managing acute, transient pain episodes that break through an established around-the-clock opioid regimen.

For research institutions, pharmaceutical laboratories, and academic investigators studying opioid pharmacology, pain-signal transduction, or analgesic drug development, the ability to order Actiq online through a trusted supplier like Cayman Chemical Company streamlines procurement while ensuring complete chain-of-custody documentation and certificates of analysis. Our inventory supports pain management research at every level, from basic science to translational studies.

Why Buy Actiq from Cayman Chemical Company?

When you shop Actiq at Cayman Chemical, you gain access to research-grade compounds manufactured and tested under stringent quality-control protocols. Each lot is accompanied by full analytical data including HPLC purity profiles, NMR spectral confirmation, and mass spectrometry verification, ensuring your downstream research relies on authentic, well-characterized material. We are committed to transparency, regulatory compliance, and scientific integrity — values that have made us a trusted partner for researchers worldwide.

Actiq fits seamlessly within a broader portfolio of fentanyl-class reference standards. You may also be interested in related compounds such as Sublimaze (2g), the classic intravenous fentanyl formulation widely used as an anesthetic adjunct and pharmacological reference, or Duragesic, the transdermal fentanyl patch system commonly studied in chronic pain and controlled-release drug-delivery research.

Key Features and Benefits of Actiq

• Rapid Transmucosal Delivery: Buccal absorption of fentanyl citrate enables fast onset analgesia, making Actiq an important model compound for studying mucosal drug delivery systems.
• High Purity Research Grade: Each batch meets strict analytical benchmarks, with purity ≥98% confirmed by HPLC, supporting reproducible experimental results.
• Comprehensive Documentation: Full certificate of analysis, SDS, and structural confirmation data provided with every order for regulatory and laboratory records.
• Versatile Research Applications: Suitable for opioid receptor binding assays, pharmacokinetic modeling, pain pathway investigations, and analgesic potency comparisons.
• Competitive Best Price Guarantee: Cayman Chemical offers transparent, market-competitive pricing on all fentanyl reference standards with no hidden fees.
• Secure, Compliant Shipping: Orders are processed under DEA Schedule II compliance frameworks and shipped with proper controlled-substance documentation and tamper-evident packaging.
• Expert Technical Support: Our team of PhD-level scientists is available to assist with protocol design, compound selection, and data interpretation.
• Broad Catalog Compatibility: Pairs well with related analytes such as Fentora (fentanyl buccal tablet) for comparative transmucosal bioavailability studies.

Specifications

Attribute	Details
Product Name	Actiq (Fentanyl Citrate Oral Transmucosal)
Active Compound	Fentanyl Citrate
CAS Number	990-73-8 (fentanyl citrate)
Molecular Formula	C₂₂H₂₈N₂O · C₆H₈O₇
Molecular Weight	528.60 g/mol (salt form)
Purity	≥98% (HPLC)
Formulation Class	Oral Transmucosal Lozenge / Fentanyl Analog
Available Doses (Reference)	200 mcg – 1600 mcg per unit
Storage Conditions	-20°C, protect from light and moisture
DEA Schedule	Schedule II Controlled Substance
Regulatory Documentation	Certificate of Analysis, SDS included
Shipping	Compliant controlled-substance packaging

Frequently Asked Questions

What is Actiq used for in pain management and opioid research?

Actiq (fentanyl citrate oral transmucosal lozenge) is clinically indicated for the management of breakthrough cancer pain in adult patients who are already tolerant to opioid therapy. In research contexts, it serves as a valuable reference standard and pharmacological tool for studying mu-opioid receptor agonism, transmucosal drug delivery kinetics, analgesic dose-response relationships, and the comparative pharmacology of fentanyl-class compounds. Researchers investigating opioid tolerance, dependence mechanisms, or novel analgesic formulations frequently include Actiq alongside related agents such as Duragesic to characterize systemic exposure profiles across different delivery routes.

How does Actiq differ from other fentanyl formulations like Fentora or Sublimaze?

While all three products share fentanyl as their active ingredient, they differ significantly in their delivery mechanisms and pharmacokinetic profiles. Actiq is an oral transmucosal lozenge that dissolves against the cheek, providing a combination of buccal and gastrointestinal absorption. Fentora is a buccal effervescent tablet designed to enhance mucosal penetration through a pH-mediated mechanism, resulting in higher bioavailability compared to Actiq. Sublimaze is an intravenous formulation used primarily in anesthesia with near-immediate systemic onset. These formulation differences make each product uniquely suited to distinct clinical scenarios and research models, particularly in comparative bioavailability and pharmacokinetic studies.

Where can I order Actiq online at the best price for laboratory research?

Cayman Chemical Company is a premier source for researchers looking to order Actiq online for legitimate scientific and analytical purposes. Our platform provides transparent pricing, verified purity documentation, and full regulatory compliance support for DEA Schedule II controlled substances. We offer competitive, best-price options with volume discount considerations for institutional buyers. All orders include a certificate of analysis and safety data sheet. To browse our complete fentanyl reference standard portfolio and place your order securely, visit our Pain Management product category page or contact our customer support team for custom procurement inquiries.

Ready to advance your opioid pharmacology or analgesic research? Shop Actiq at Cayman Chemical Company today and benefit from industry-leading purity standards, rigorous documentation, and the support of an expert scientific team. Whether you are running receptor binding studies, developing novel pain therapeutics, or conducting forensic reference analysis, our research-grade Actiq provides the reliability your work demands. Buy Actiq now at the best price available, and experience the Cayman Chemical difference — where scientific excellence meets seamless procurement. Contact us or add to cart to get started.