Overview of U-47700
U-47700 — sometimes referred to in scientific literature as “Pink” or “U4” — is a synthetic opioid research compound first synthesized by scientists at The Upjohn Company during the 1970s as part of a broader investigation into non-morphine analgesic scaffolds. As a member of the Legacy Synthetic Opioid class, U-47700 exhibits high-affinity binding to the mu-opioid receptor (MOR), making it an invaluable tool compound for researchers investigating opioid receptor pharmacology, pain pathway signaling, and the structure-activity relationships (SAR) of benzamide-class opioids.
Chemically characterized as 3,4-Dichloro-N-[2-(dimethylamino)cyclohexyl]-N-methylbenzamide, U-47700 possesses a molecular formula of C14H20Cl2N2O and a molecular weight of approximately 329.2 g/mol. Its distinct dichlorobenzamide scaffold differentiates it structurally from classical opioids such as morphine or fentanyl, offering researchers a unique chemical probe for comparative receptor binding studies. When you buy U-47700 from Cayman Chemical Company, you receive a certified reference standard supported by full analytical documentation including NMR, HPLC purity data, and a Certificate of Analysis (CoA).
This compound is intended strictly for in vitro research, forensic reference, and analytical laboratory use only. It is not for human or veterinary consumption. Researchers working in toxicology, forensic chemistry, and pharmacology will find U-47700 for sale here as an authenticated standard that meets rigorous quality benchmarks essential for reproducible scientific results.
Key Features and Benefits of U-47700
- High Analytical Purity: Each lot of U-47700 is manufactured and tested to ensure ≥98% purity by HPLC, providing reliable and reproducible data in receptor binding and analytical assays.
- Comprehensive Documentation: Supplied with a full Certificate of Analysis, NMR spectral data, and mass spectrometry confirmation — critical for forensic and pharmacological research workflows.
- Mu-Opioid Receptor Reference Standard: Ideal as a positive control or comparative reference in MOR binding assays, radioligand displacement studies, and functional activity screening.
- Unique Benzamide Scaffold: The dichlorobenzamide structural motif offers a chemically distinct probe compared to phenylpiperidine or morphinan opioids, broadening SAR research scope.
- Forensic Analysis Support: Widely used as a certified reference material in forensic toxicology laboratories for the identification and quantification of U-47700 in biological matrices.
- Competitive Pricing: We offer U-47700 at the best price without compromising on quality — making professional-grade research accessible to academic, government, and private laboratories alike.
- Reliable Fulfillment: When you order U-47700 online through Cayman Chemical Company, benefit from fast processing, secure packaging, and tracked shipping to qualified research institutions.
Researchers exploring the U-Series opioid landscape may also be interested in MPPP (2g), another important legacy synthetic opioid reference compound available in our catalog, useful for comparative neuropharmacological studies.
Specifications
| Attribute | Details |
|---|---|
| Chemical Name | 3,4-Dichloro-N-[2-(dimethylamino)cyclohexyl]-N-methylbenzamide |
| Molecular Formula | C₁₄H₂₀Cl₂N₂O |
| Molecular Weight | ~329.2 g/mol |
| CAS Number | 82657-23-6 |
| Purity | ≥98% (HPLC) |
| Appearance | White to off-white crystalline powder |
| Storage Conditions | Store at -20°C, protected from light and moisture |
| Solubility | Soluble in DMSO, ethanol, and methanol |
| Primary Target | Mu-Opioid Receptor (MOR) Agonist |
| Application | Forensic reference standard, receptor pharmacology, SAR studies |
| Regulatory Status | For research use only — not for human or veterinary use |
Frequently Asked Questions
What is U-47700 used for in scientific research?
U-47700 is primarily used as a mu-opioid receptor (MOR) agonist reference standard in pharmacological and forensic research settings. Scientists employ it in radioligand binding assays, functional receptor activity studies, and structure-activity relationship (SAR) investigations of benzamide-class opioids. It also serves as an authenticated reference material in forensic toxicology laboratories for identifying and quantifying the compound in biological specimens such as blood, urine, and tissue samples. Its unique dichlorobenzamide scaffold makes it particularly valuable for comparative studies against classical opioids.
How does U-47700 compare to other legacy synthetic opioids like MPPP?
While both U-47700 and MPPP (2g) are classified as legacy synthetic opioid research compounds, they differ significantly in their chemical scaffolds and receptor interaction profiles. U-47700 is a benzamide-class MOR agonist, whereas MPPP belongs to the 4-phenylpiperidine class and is structurally related to meperidine. This makes them complementary reference tools: researchers studying opioid receptor diversity, selectivity profiling, or multi-compound forensic panels will benefit from having both compounds available. Together they support a broader understanding of synthetic opioid pharmacology across different structural classes found in the Legacy Synthetic Opioid category.
Where can I buy U-47700 at the best price for laboratory use?
Cayman Chemical Company is a trusted source to shop U-47700 for verified research-grade quality. When you order U-47700 online here, you receive a compound backed by rigorous analytical testing, a full Certificate of Analysis, and professional customer support. We offer U-47700 for sale at competitive, transparent pricing with no hidden fees, making it accessible for academic institutions, government forensic labs, and pharmaceutical research organizations. All orders are fulfilled with appropriate documentation to support your compliance and record-keeping requirements. Always ensure you possess the necessary institutional authorization and comply with all applicable local, national, and international regulations before purchasing controlled or scheduled research compounds.
Ready to advance your opioid receptor research? Shop U-47700 today at Cayman Chemical Company and experience the confidence that comes with research-grade purity, comprehensive analytical documentation, and industry-leading customer service. Whether you need a forensic reference standard or a pharmacological probe for MOR binding studies, we have you covered. Browse our full Legacy Synthetic Opioid catalog to discover additional reference compounds that complement your research program. Place your order now and take advantage of our best price guarantee on certified synthetic opioid research standards.


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