Overview of Lomotil
Lomotil is a well-established pharmaceutical compound recognized globally for its role in managing acute and chronic diarrhea. Composed of diphenoxylate hydrochloride and atropine sulfate, Lomotil works by acting on the mu-opioid receptors in the intestinal tract, effectively reducing peristaltic activity and increasing transit time. This dual-action formulation has made it a cornerstone compound in both clinical medicine and pharmacological research. When you shop Lomotil through Cayman Chemical Company, you gain access to a product backed by rigorous quality controls and complete analytical documentation suitable for laboratory and reference use.
As part of the broader category of Digestive Health and Anti-Diarrheal compounds, Lomotil occupies a unique position within the phenylpropylamine class. Researchers studying gastrointestinal motility, opioid receptor pharmacology, or antidiarrheal drug mechanisms will find this compound to be an invaluable reference standard. Its well-characterized pharmacokinetic profile, combined with decades of clinical data, makes Lomotil one of the most studied molecules in its category.
Why Buy Lomotil from Cayman Chemical Company?
Key Features and Benefits
- Dual Active Ingredients: Contains diphenoxylate HCl and atropine sulfate for a synergistic antidiarrheal mechanism, reducing both intestinal motility and secretion.
- High Purity Standard: Each batch undergoes stringent analytical testing including HPLC and mass spectrometry to ensure consistent purity for research-grade applications.
- Phenylpropylamine Classification: Belongs to the phenylpropylamine structural class, making it highly relevant for structure-activity relationship (SAR) studies and receptor binding assays.
- Comprehensive Documentation: Comes with a Certificate of Analysis (CoA), Safety Data Sheet (SDS), and detailed spectral data for full traceability.
- Fast and Secure Shipping: Orders are carefully packaged and dispatched promptly, ensuring product integrity upon arrival.
- Competitive Pricing: Find Lomotil for sale at one of the most competitive price points available for research-grade chemical standards.
- Trusted Brand: Cayman Chemical is a globally recognized supplier of biochemicals, trusted by researchers, institutions, and pharmaceutical companies worldwide.
- Ideal for Reference Standards: Suitable for use in pharmaceutical quality control, metabolite identification, and bioanalytical method development.
Specifications
| Attribute | Details |
|---|---|
| Chemical Name | Diphenoxylate Hydrochloride / Atropine Sulfate |
| CAS Number | 3810-80-8 (Diphenoxylate HCl) |
| Molecular Formula | C₃₀H₃₂N₂O₂ · HCl (Diphenoxylate HCl) |
| Molecular Weight | 489.06 g/mol (Diphenoxylate HCl) |
| Purity | ≥98% (HPLC) |
| Appearance | White to off-white crystalline powder |
| Storage Conditions | Room temperature, away from light and moisture |
| Application | Antidiarrheal research, receptor pharmacology, reference standard |
| Classification | Phenylpropylamine / Opioid Receptor Agonist |
Frequently Asked Questions
What is Lomotil used for in pharmacological research?
Lomotil is primarily used in pharmacological research to study mu-opioid receptor activity in the gastrointestinal system. Its active component, diphenoxylate, binds to opioid receptors in the intestinal wall, reducing peristalsis and fluid secretion. This makes it an excellent model compound for investigating antidiarrheal drug mechanisms, opioid receptor selectivity, and structure-activity relationships within the phenylpropylamine class. Researchers also use it as a certified reference standard for bioanalytical and quality control testing in pharmaceutical development pipelines.
How does Lomotil compare to other antidiarrheal compounds like Dolophine or Methadose?
While Lomotil targets peripheral mu-opioid receptors in the gut with limited CNS penetration, compounds such as Dolophine and Methadose (both methadone formulations) are primarily central opioid analgesics used in pain management and opioid dependence treatment. The key distinction lies in receptor distribution and therapeutic target: Lomotil is designed to minimize systemic opioid effects while maximizing local GI action, making it uniquely suitable for antidiarrheal research. Researchers studying comparative opioid pharmacology may also find L-Polamidon a valuable parallel reference in their studies.
Where can I order Lomotil online at the best price with guaranteed quality?
You can order Lomotil online directly through Cayman Chemical Company’s secure e-commerce platform. We offer Lomotil for sale with full analytical documentation, ensuring your research meets the highest standards of reproducibility and compliance. Our pricing is highly competitive within the research chemicals market, and bulk order discounts may be available for institutional purchasers. Every order is fulfilled with careful packaging, real-time tracking, and responsive customer support to guarantee a seamless purchasing experience from checkout to delivery.
Ready to buy Lomotil at the best price? Add it to your cart today and benefit from Cayman Chemical Company’s industry-leading quality assurance, fast dispatch, and comprehensive technical support. Whether you’re advancing GI motility research, developing bioanalytical methods, or building your reference standard library, Lomotil from Cayman Chemical is the smart, reliable choice. Shop Lomotil now and join thousands of researchers worldwide who trust Cayman Chemical for their most critical compound needs.


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