Protonitazene

Overview of Protonitazene

Protonitazene (chemical designation: 2-methyl-3-[2-(4-propoxybenzyl)-5-nitrobenzimidazol-1-yl]propan-1-ol) is a potent synthetic opioid belonging to the benzimidazole-opioid (nitazene) family of compounds. First synthesized in the mid-twentieth century alongside related analogs, Protonitazene has gained renewed scientific interest as researchers investigate the structural pharmacology of novel opioid formulations. Its unique benzimidazole core differentiates it from classical morphinan or phenylpiperidine opioids, making it a particularly valuable tool for studying mu-opioid receptor (MOR) agonism, ligand-binding kinetics, and downstream signal transduction pathways.

If you are looking to shop Protonitazene for legitimate scientific, forensic, or analytical research, Cayman Chemical Company offers one of the most reliable sources on the market. Our reference standards are manufactured to meet exacting purity thresholds, with full certificate of analysis (CoA) documentation provided with every order. Whether you are a toxicologist developing detection assays, a pharmacologist mapping opioid receptor pharmacodynamics, or an analytical chemist validating LC-MS/MS methods, our Protonitazene for sale meets the rigorous demands of modern laboratory science.

Browse our full Novel Opioid Formulations catalog to discover additional synthetic opioid reference standards for your research program.

Key Features and Benefits of Protonitazene

• High Analytical Purity: Each lot is tested to ≥98% purity by HPLC, ensuring minimal interference in sensitive assays.
• Comprehensive Documentation: Full certificate of analysis, NMR spectral data, and mass spectrometry confirmation provided with every shipment.
• Research-Grade Quality: Manufactured under stringent quality management protocols suitable for peer-reviewed publication and regulatory submissions.
• Versatile Application: Suitable for receptor binding studies, in vitro pharmacology, forensic reference standard development, and method validation workflows.
• Stable Formulation: Available as a neat solid or in certified solvent solutions; proper storage ensures long shelf-life integrity.
• Competitive Pricing: We offer the best price on high-quality Protonitazene without compromising on purity or documentation standards.
• Fast Order Fulfillment: Order Protonitazene online today and benefit from streamlined order processing and reliable international shipping options.
• Expert Scientific Support: Our team of PhD-level chemists and pharmacologists is available to assist with technical inquiries and custom research requirements.

You may also find our related compound Etodezitramide valuable for comparative structure-activity relationship studies within the synthetic opioid class.

Specifications

Attribute	Detail
Product Name	Protonitazene
CAS Number	119276-01-6
Molecular Formula	C₂₂H₂₈N₄O₄
Molecular Weight	428.5 g/mol
Purity	≥98% (HPLC)
Appearance	White to off-white solid
Solubility	Soluble in DMSO, methanol, ethanol
Storage Conditions	-20°C, protected from light and moisture
Compound Class	Benzimidazole Synthetic Opioid (Nitazene)
Application	Analytical Reference Standard, Pharmacological Research
Available Quantities	1 mg, 5 mg, 10 mg
Shipping	Ambient; dry ice available upon request

Frequently Asked Questions

What is Protonitazene used for in scientific research?

Protonitazene is primarily used as an analytical reference standard and pharmacological research tool. Researchers utilize it to study mu-opioid receptor agonism, investigate benzimidazole-class opioid structure-activity relationships (SAR), and develop forensic detection methods such as immunoassay and LC-MS/MS confirmation protocols. It is also employed in in vitro binding assays, radioligand displacement studies, and comparative potency evaluations within the nitazene synthetic opioid subclass. All purchases are intended solely for legitimate research applications in properly licensed laboratory settings.

How does Protonitazene compare to other novel synthetic opioids like Etodezitramide?

While both Protonitazene and Etodezitramide are classified as novel synthetic opioid compounds, they differ significantly in their core scaffold and receptor interaction profiles. Protonitazene belongs to the benzimidazole-opioid (nitazene) series characterized by a bicyclic heterocyclic core, whereas Etodezitramide is a desmethyl prodrug analog with distinct pharmacokinetic properties. Researchers studying opioid receptor pharmacology often acquire both compounds for side-by-side comparative analysis, enabling a more complete understanding of structural requirements for MOR agonist activity and selectivity.

Where can I buy Protonitazene online at the best price with guaranteed purity?

You can buy Protonitazene online directly through Cayman Chemical Company, one of the most trusted suppliers of novel opioid formulations and research-grade reference standards in the industry. Every batch of our Protonitazene for sale is accompanied by a certificate of analysis confirming ≥98% HPLC purity, full spectroscopic data, and lot-specific quality documentation. We offer competitive, best price tiered pricing based on quantity, with secure online ordering, multiple payment options, and expedited shipping to qualified research institutions and licensed laboratories worldwide. Order Protonitazene online today through our secure checkout portal for fast and reliable delivery.

Order Protonitazene Today

Don’t miss the opportunity to advance your opioid receptor research with one of the most sought-after benzimidazole-class reference standards available. When you shop Protonitazene at Cayman Chemical Company, you invest in uncompromising quality, comprehensive analytical documentation, and the backing of a world-class scientific team. Whether you need a small quantity for method development or larger lots for ongoing pharmacological studies, we have the right solution at the right price. Buy Protonitazene now and experience the Cayman Chemical difference — precision, reliability, and scientific excellence in every milligram. Visit our Novel Opioid Formulations page to explore our full catalog of synthetic opioid reference standards and place your order today.